A new manuscript by Willett, Koder and Banta explores the apparent reversibility of NAD+ kinase enzymes. Animal forms of the enzyme are found to be reversible and this work demonstrates the human form is apparently irreversible due to strong product inhibition by NAD+. These enzymes are useful for the interconversion of NAD+ and NADP+ and reversible forms could also be useful in ATP regeneration applications. The new results were published in Biochemistry.
Professor Banta gave a seminar entitled “Engineering of Acidithiobacillus ferrooxidans for biofuel, biomining and biotechnology applications” in the Department of Energy, Environmental, and Chemical Engineering at Washington University, St. Louis, MO